WHOLESOME CLINIC
Integrative Psychiatry & Wellness
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In-person care in Frisco, TX • Telehealth in TX, CO, NM, OK, LA , OR & AR
Weight Loss Medications

Understanding Weight Loss Medications: A Comprehensive Guide

If you’ve been working on diet, exercise, and lifestyle changes but still feel stuck, prescription weight loss medication may be an option. Below is a clear overview of how they work, who they’re for, and what to expect—so you can make an informed decision with your provider.

Typical results: ~5–10% of starting body weight in 12 months Best with lifestyle changes Ongoing check-ins recommended

Is GLP-1 Right For You?

GLP-1 medications can be powerful tools for appetite regulation and metabolic health—but they’re not right for everyone. Review the sections below and schedule a visit to discuss options tailored to your goals and medical history.

GLP-1 Treatment Guides

Explore Semaglutide and Tirzepatide Options

Choose the path that best fits how you want to receive care. Wholesome Clinic has dedicated pages for local Frisco-area treatment and Texas telehealth evaluations.

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Frisco Local Care

Semaglutide in Frisco, TX

Learn about semaglutide evaluations, pricing, eligibility, and local medical weight loss care for patients in Frisco and nearby North Texas communities.

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Texas Telehealth

Semaglutide Telehealth Texas

Explore online semaglutide evaluations for eligible patients located in Texas, including medication options, lab review, pricing, and follow-up care.

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Frisco Local Care

Tirzepatide in Frisco, TX

Learn about tirzepatide, Zepbound®, compounded options, pricing, eligibility, and medical weight loss evaluations available through our Frisco-area care pathway.

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Texas Telehealth

Tirzepatide Telehealth Texas

Review online tirzepatide evaluations, Zepbound® discussion, medication pricing, eligibility, labs, and follow-up care for eligible Texas patients.

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These pages help patients compare local Frisco care and Texas telehealth options for semaglutide and tirzepatide. Medication eligibility is determined after clinical evaluation, medication review, and lab review.

What Are Weight Loss Medications?

Weight loss medications (anti-obesity drugs) are prescription options designed to support weight reduction by reducing appetite, increasing fullness, or limiting fat absorption. They are most effective when combined with a healthy diet and regular physical activity.

Who Can Benefit from Weight Loss Medications?

Weight loss medications are generally prescribed for individuals who:

  • Have a Body Mass Index (BMI) of 30 or higher (classified as obesity).
  • Have a BMI of 27 or higher with weight-related health conditions such as type 2 diabetes, high blood pressure, or sleep apnea.

Your healthcare provider will assess your medical history, current health conditions, and goals to determine the best fit.

How Do Weight Loss Medications Work?

Depending on the medication, they may work by:

  • Appetite Suppressants: Reduce appetite and increase fullness (e.g., phentermine, bupropion-naltrexone).
  • Fat Absorption Blockers: Reduce absorption of dietary fat (e.g., orlistat).
  • GLP-1 Receptor Agonists: Mimic GLP-1 to regulate appetite and blood sugar (e.g., semaglutide).
  • Combination Medications: Combine mechanisms to enhance effect (e.g., bupropion-naltrexone).

Commonly Prescribed Weight Loss Medications

Below are commonly prescribed options in the U.S. (availability and suitability vary by patient).

Phentermine

Short-term (up to 12 weeks)
Who it’s for: Individuals without significant cardiovascular risks.
Common side effects: Increased heart rate, dry mouth, insomnia.

Orlistat (Alli, Xenical)

Long-term option
Who it’s for: Those seeking a long-term solution.
Common side effects: GI discomfort, oily stools.

Bupropion–Naltrexone (Contrave)

Cravings + appetite
Who it’s for: Individuals with emotional eating patterns.
Common side effects: Nausea, dizziness, increased blood pressure.

Liraglutide (Saxenda)

Daily injectable
Who it’s for: Adults with obesity or overweight with weight-related conditions.
Common side effects: Nausea, diarrhea, constipation.

Semaglutide (Wegovy)

Weekly injectable (GLP-1)
Who it’s for: Adults with obesity or overweight with weight-related conditions..
Common side effects: Nausea, diarrhea, constipation, fatigue.

Tirzepatide (ZEPBOUND)

Weekly injectable (GLP-1 + GIP)
Who it’s for: Adults with obesity or overweight and related conditions.
Common side effects: Nausea, vomiting, diarrhea, decreased appetite.

Diethylpropion

Short-term
Who it’s for: Individuals seeking short-term appetite reduction support.
Common side effects: Increased heart rate, dizziness, dry mouth, insomnia.

Are Weight Loss Medications Safe?

These medications are generally safe when prescribed and monitored by a healthcare professional. As with any medication, side effects can occur. Common side effects include nausea/vomiting, constipation/diarrhea, headaches, and increased heart rate or blood pressure. Your provider will discuss risks vs. benefits and monitor your progress.

What to Expect with Weight Loss Medications

  • Gradual weight loss: Many people lose about 5–10% of body weight within the first year when paired with lifestyle changes.
  • Ongoing monitoring: Regular check-ins help track progress, manage side effects, and adjust treatment.
  • Lifestyle changes: Best results come from diet, exercise, and behavior support alongside medication.

How to Maximize Results

  • Balanced diet: Whole foods, lean proteins, healthy fats, fruits and vegetables.
  • Stay active: Aim for at least 150 minutes of moderate exercise weekly.
  • Get support: Consider a support group or working with a dietitian.
  • Track progress: Use an app or journal for food, movement, and weight changes.

Are Weight Loss Medications Covered by Insurance?

Coverage varies by plan. Some insurers cover weight loss medications when considered medically necessary for obesity-related conditions. Check with your insurance provider to understand coverage and out-of-pocket costs.

Frequently Asked Questions (FAQs)

Are weight loss medications a permanent solution?

They’re tools that can help—long-term success still depends on maintaining healthy lifestyle habits.

Can I stop taking weight loss medications once I reach my goal?

Stopping can lead to weight regain. Discuss maintenance options and next steps with your provider.

Are there natural alternatives to weight loss medications?

Lifestyle changes are the foundation. Medications can provide additional support for people with obesity or weight-related health conditions.

*Results vary by person. This page is for education only and does not replace medical advice. Always consult a licensed clinician for personalized guidance.

Medical Weight Loss Medications