Medication Genetic Testing (Pharmacogenomics) for Personalized Mental Health Care

Medication Genetic Testing (pharmacogenomic / PGx) uses a small DNA sample to analyze how your body may metabolize and respond to certain psychiatric medications. This can help your clinician make more informed medication and dosing decisions - especially if you’ve had side effects, limited benefit, or multiple medication trials.

The test is simple and painless (cheek swab) and can typically be completed in minutes.

1. Book a New Mental Health Visit: We review your history, current medications, and goals and decide if PGx testing is appropriate.
2. Swab collection: A simple cheek swab is completed in-office or through a mailed kit.
3. Lab analysis: Your DNA is analyzed for medication metabolism and drug-gene interactions.
4. Report received: A detailed report is delivered to your provider.
5. Results review: We review your report during a Follow-up Mental Health Visit and adjust your plan when clinically appropriate.

• Depression or Treatment-Resistant Depression
• Anxiety or panic disorder
• ADHD (as part of a broader evaluation and treatment plan)
• Bipolar disorder
• PTSD
• OCD
• History of medication side effects or poor response

Testing is not required for everyone. We’ll recommend it when it’s likely to meaningfully inform medication decisions.

Many commercial insurance plans cover or partially cover pharmacogenomic testing, depending on your plan and medical necessity. Coverage varies.

What to Expect (Billing & Insurance)

1. We submit your insurance information when the test is ordered.
2. When you receive your kit, we recommend calling GeneSight to confirm any coverage or billing questions.
3. We review results during a Follow-up Mental Health Visit and adjust treatment when clinically appropriate.

Note: Wholesome Clinic does not control insurance determinations or GeneSight billing policies.

Is genetic medication testing painful?

No. It uses a simple cheek swab that typically takes less than a minute.

How long do results take?

Results are often available within 7–10 business days, though timing can vary.

Can this test tell me which medication will work 100%?

No. PGx testing does not guarantee a perfect match, but it can provide useful data to reduce trial-and-error.

Do I still need regular appointments?

Yes. PGx testing supports medication planning, but follow-ups are still needed to monitor response and adjust care.